Chemical study of the medicinal plant "Toe" (Datura sanguinea (R.& P.) D. Don)
DOI:
https://doi.org/10.21754/tecnia.v17i2.374Keywords:
scopolamine, datura sanguine, medicinal plant toe, tropanic alkaloidsAbstract
From the leaves, flowers and seeds of the Toe or "Misha Toro" (Datura Sanguino (R. & P.) D.Don), a plant collected in the Province of Huancabamba (Department of Piura, in the northern highlands of Peru) was isolated the alkaloid scopolamine, which was identified by its mass spectra, RMN1H and RMN13C. In addition, the qualitative analysis of the secondary metabolites and the quantification of alkaloids present in the different organs of this plant were carried out.
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References
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[2] Griffin, W., Lin, D., “Chemotaxonomy and geographical distribution of tropane alkaloids”, Phytochemistry, Vol. 53, pp. 623-637 (2000), USA.
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[5] De Feo, V., “Medicinal and magical plants in the northern Peruvian Andes”, Fitoterapia, pp, Vol. 63, 417-440, 1992, España.
[6] Schultes, R., Raffauf, R., “The Healing Forest, Dioscorides Press”, pp. 419-24,1990, Oregon, USA.
[7] Evans, W., Major, V., Pe Than, M., “The Alkaloids of the Genus Datura, Section Brugmansia. Part III. Datura sanguinea R. and P.", Planta Médica, Vol. 13, pp. 353-358 (1965), Alemania.
[8] Evans, W., Major, V., “The alkaloids of the genus Datura, section Brugmansia. Part IV. New Alkaloids of D. sanguinea R. and P”, J. Chem. Soc., pp. 1621-1623 (1966), Inglaterra.
[9] Evans, W., Major, V., “The alkaloids of the genus Datura, section Brugmansia. Part V. Alkaloids of D. sanguinea R. and P. and related esters of Tropane-3α, 6β, 7β-triol", J. Chem. Soc., pp. 2775-2778 (1968), Inglaterra.
[10] Leary, J., “Alkaloids of the seeds of Datura sanguinea”, Lloydia, Vol. 33, pp. 264-266 (1970), USA.
[11] Drey, R,, Foster, G., “The Estimation of Tropane Alkaloids in Vegetable Drugs by Paper Partition Chromatography, with Special Reference to the Alkaloids of Datura sanguinea”, J. Pharm. Pharmacol., Vol. 5, pp.
839-848 (1953), Inglaterra.
[12] Reyna, V., Torpoco V., Cóndor E., “Estudio Químico de las semillas del Toe (Brugmansia sanguinea R, & P.)”, Rev. Soc. Quím. Vol. 70, pp. 188 — 200 (2004), Lima - Perú.
[13] Reyna, V., Muedas G,, Collantes, I., Moreno, P., “Estudio Químico de las Hojas del Toe (Datura sanguinea (R. & P.) D. Don)”, Rev. Soc. Quím. Vol. 72, pp.74-85 (2006), Lima — Perú.
[14] Rondina R., Coussio, J., “Estudio Fitoquímico de Plantas medicinales”, Revista de Investigaciones Agropecuarias-INTA, Serie 2, Vol. VI, Nro. 33, pp. 351-366 (1969), Argentina.
[15] Pelt, J. M., Vigneron, Cl. et Younos, Ch., "Comparaison de diverses méthodes officielle utilisées pour le dosage des Alcaloides des Solanacées", Bull. Soc. Pharm. Nancy, Vol. 72, pp. 12-23 (1967), Francia.
[16] Sarazin, C., Goethals, G., Séquin, J., Barbotin, J., “Spectral reassignment and structure elucidation of scopolamine free base through two —dimensional NMR techniques”, Magnetic Resonance in Chemistry, Vol. 29,
pp. 291-300, (1991), Reino Unido.
[2] Griffin, W., Lin, D., “Chemotaxonomy and geographical distribution of tropane alkaloids”, Phytochemistry, Vol. 53, pp. 623-637 (2000), USA.
[3] Polia, M., “Despierta, remedio, cuenta: adivinos y médicos del Ande”, Tomo 1, PUCP, pp. 333-346, 1996, Lima - Perú.
[4] Camino, L., Cerros, “Plantas y Lagunas Poderosas, La medicina al norte del Perú”, CIPCA, pp. 296, 1992, Piura - Perú.
[5] De Feo, V., “Medicinal and magical plants in the northern Peruvian Andes”, Fitoterapia, pp, Vol. 63, 417-440, 1992, España.
[6] Schultes, R., Raffauf, R., “The Healing Forest, Dioscorides Press”, pp. 419-24,1990, Oregon, USA.
[7] Evans, W., Major, V., Pe Than, M., “The Alkaloids of the Genus Datura, Section Brugmansia. Part III. Datura sanguinea R. and P.", Planta Médica, Vol. 13, pp. 353-358 (1965), Alemania.
[8] Evans, W., Major, V., “The alkaloids of the genus Datura, section Brugmansia. Part IV. New Alkaloids of D. sanguinea R. and P”, J. Chem. Soc., pp. 1621-1623 (1966), Inglaterra.
[9] Evans, W., Major, V., “The alkaloids of the genus Datura, section Brugmansia. Part V. Alkaloids of D. sanguinea R. and P. and related esters of Tropane-3α, 6β, 7β-triol", J. Chem. Soc., pp. 2775-2778 (1968), Inglaterra.
[10] Leary, J., “Alkaloids of the seeds of Datura sanguinea”, Lloydia, Vol. 33, pp. 264-266 (1970), USA.
[11] Drey, R,, Foster, G., “The Estimation of Tropane Alkaloids in Vegetable Drugs by Paper Partition Chromatography, with Special Reference to the Alkaloids of Datura sanguinea”, J. Pharm. Pharmacol., Vol. 5, pp.
839-848 (1953), Inglaterra.
[12] Reyna, V., Torpoco V., Cóndor E., “Estudio Químico de las semillas del Toe (Brugmansia sanguinea R, & P.)”, Rev. Soc. Quím. Vol. 70, pp. 188 — 200 (2004), Lima - Perú.
[13] Reyna, V., Muedas G,, Collantes, I., Moreno, P., “Estudio Químico de las Hojas del Toe (Datura sanguinea (R. & P.) D. Don)”, Rev. Soc. Quím. Vol. 72, pp.74-85 (2006), Lima — Perú.
[14] Rondina R., Coussio, J., “Estudio Fitoquímico de Plantas medicinales”, Revista de Investigaciones Agropecuarias-INTA, Serie 2, Vol. VI, Nro. 33, pp. 351-366 (1969), Argentina.
[15] Pelt, J. M., Vigneron, Cl. et Younos, Ch., "Comparaison de diverses méthodes officielle utilisées pour le dosage des Alcaloides des Solanacées", Bull. Soc. Pharm. Nancy, Vol. 72, pp. 12-23 (1967), Francia.
[16] Sarazin, C., Goethals, G., Séquin, J., Barbotin, J., “Spectral reassignment and structure elucidation of scopolamine free base through two —dimensional NMR techniques”, Magnetic Resonance in Chemistry, Vol. 29,
pp. 291-300, (1991), Reino Unido.
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Published
2007-12-01
How to Cite
[1]
V. Reyna Pinedo and E. Cóndor Cuyubamba, “Chemical study of the medicinal plant ‘Toe’ (Datura sanguinea (R.& P.) D. Don)”, TEC, vol. 17, no. 2, pp. 71–78, Dec. 2007.
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